ea0065p282 | Neuroendocrinology | SFEBES2019
Seejore Khyatisha
, Tudawe Gireesha
, Mansoor Tihami
, Lynch Julie M
, Orme Stephen M
, Phillips Nick
, Tyagi Atul
, Flatley Michael
, Loughrey Carmel
, Murray Robert D
Introduction: Radiotherapy (RT) can achieve tumour control rates of over 90% in patients with pituitary adenomas. The commonest toxicity of irradiation is hypopituitarism. The exact incidence is variable and requires long-term intermittent testing for deficiency of all hypothalamic−pituitary axes (HPA). The aim of this study is to determine the time to onset of individual hormonal deficiencies and establish a time frame for endocrine testing during follow-up post-RT....